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dc.contributor.authorKurt, Pınaren_US
dc.contributor.authorEmek Savaş, Derya Durusuen_US
dc.contributor.authorBatum, Kübraen_US
dc.contributor.authorTurp, Bilgeen_US
dc.contributor.authorGüntekin, Baharen_US
dc.contributor.authorKarşıdağ, Sibelen_US
dc.contributor.authorGülmen Yener, Görseven_US
dc.date.accessioned2016-04-01T12:57:50Z
dc.date.available2016-04-01T12:57:50Z
dc.date.issued2014
dc.identifier.citationKurt, P., Emek Savaş, D. D., Batum, K., Turp, B., Güntekin, B., Karşıdağ, S., Gülmen Yener, G. (2014). Auditory event related delta responses are reduced in patients with mild cognitive impairment. Behavioural Neurology. 2014, 1-11.en_US
dc.identifier.issn0953-4180
dc.identifier.urihttps://hdl.handle.net/20.500.12294/267
dc.identifier.urihttp://dx.doi.org/10.1155/2014/268967
dc.descriptionKurt, Pınar (Arel Author)en_US
dc.description.abstractBackground. Event-related oscillations (ERO) may provide a useful tool for the identification of cognitive deficits in mild cognitive impairment (MCI) and Alzheimer's disease (AD). In the present study, we investigate peak-to-peak amplitude of auditory eventrelated delta oscillations of MCI subjects. Method. The study included twenty-two consecutive patients with MCI recruited in neurology clinic and 21 age- and education-matched normal elderly controls. A classical auditory oddball paradigm was used in the experiments. EEG was recorded from F3, Fz, F4, C3, Cz, C4, P3, Pz, P4, O1, Oz, and O2 locations. The maximum peak-to-peak amplitudes for each subject's averaged delta response (0.5-2.2 Hz) were measured. Results. The amplitudes between groups differed significantly at the frontal and mid-centroparietal locations. ANOVA on delta responses revealed a significant effect for groups (F(1.41) = 4.84, P = 0.033), indicating a larger delta response for healthy controls than MCI subjects. Post hoc comparisons revealed that peak-to-peak delta response was significantly larger for healthy controls than for MCI over electrode sites F3, Fz, F4, Cz, C4, and Pz. Discussion. Event-related delta frequency band seems to be the most affected oscillatory response in cognitive impairment due to AD. Therefore, it deserves to be investigated as a candidate electrophysiological biomarker in further studies.en_US
dc.language.isoengen_US
dc.publisherHindawi Publishingen_US
dc.relation.ispartofBehavioural Neurologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPatientsen_US
dc.subjectAuditory Evoked Responseen_US
dc.subjectOscillationsen_US
dc.subjectAmplitude Estimationen_US
dc.subjectAlzheimer's Patientsen_US
dc.subjectMild Cognitive Impairmenten_US
dc.titleAuditory event related delta responses are reduced in patients with mild cognitive impairmenten_US
dc.typearticleen_US
dc.departmentİstanbul Arel Üniversitesi, Fen Edebiyat Fakültesi, Psikoloji Bölümü.en_US
dc.authoridTR24351en_US
dc.authoridTR227002en_US
dc.authoridTR204666en_US
dc.authoridTR9297en_US
dc.authoridTR143760en_US
dc.identifier.volume2014en_US
dc.identifier.startpage1en_US
dc.identifier.endpage11en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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