Başlık için PubMed İndeksli Yayınlar Koleksiyonu listeleme
Toplam kayıt 288, listelenen: 123-142
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Gene therapy in haemophilia: literature review and regional perspectives for Turkey
(SAGE Publications Ltd, 2022)Haemophilia is an X-linked lifelong congenital bleeding disorder that is caused by insufficient levels of factor VIII (FVIII; haemophilia A) or factor IX (FIX; haemophilia B) and characterized by spontaneous and trauma-related ... -
Genes and molecular mechanisms involved in the epileptogenesis of idiopathic absence epilepsies
(Elsevier, 2012)Idiopathic absence epilepsies (IAE), that have high prevalence particularly among children and adolescents, are complex disorders mainly caused by genetic factors. Childhood absence epilepsy and juvenile absence epilepsy ... -
Genome-Guided Mass Spectrometry Expedited the Discovery of Paraplantaricin TC318, a Lantibiotic Produced byLactobacillus paraplantarumStrain Isolated From Cheese
(Frontiers Media SA., 2020)The quest for potent alternatives to the currently used antimicrobials is urged by health professionals, considering the rapid rise in resistance to preservatives and antibiotics among pathogens. The current study was ... -
Germline mutational variants of Turkish ovarian cancer patients suspected of Hereditary Breast and Ovarian Cancer (HBOC) by next-generation sequencing
(Elsevier GmbH, 2024)Hereditary Breast and Ovarian Cancer (HBOC) syndrome is characterized by an increased risk of developing breast cancer (BC) and ovarian cancer (OC) due to inherited genetic mutations. Understanding the genetic variants ... -
Granulomatous annular diseases
(Elsevier Inc., 2023)Granulomatous skin disorders comprise a large group of diseases that are typically characterized by granuloma formation both in the skin and in many other tissues. Cutaneous lesions are usually seen as erythematous papules ... -
Habit reversal training and educational group treatments for children with tourette syndrome: A preliminary randomised controlled trial
(Elsevier, 2016)Quality of life of children with Tourette Syndrome (TS) is impacted greatly by its symptoms and their social consequences. Habit Reversal Training (HRT) is effective but has not, until now, been empirically evaluated in ... -
Hair Loss Profiles and Ritlecitinib Efficacy in Patients with Alopecia Areata: Post Hoc Analysis of the ALLEGRO Phase 2b/3 Study
(ADIS INT LTD, 2023)IntroductionRitlecitinib demonstrated efficacy in patients with alopecia areata (AA) in the ALLEGRO phase 2b/3 study (NCT03732807). However, hair loss presentation may vary based on location (e.g., scalp, eyebrow/eyelash, ... -
Heterogeneity of sensitization profiles and clinical phenotypes among patients with seasonal allergic rhinitis in Southern European countries-The @IT.2020 multicenter study
(John Wiley and Sons Inc, 2024)Background: Pollen allergy poses a significant health and economic burden in Europe. Disease patterns are relatively homogeneous within Central and Northern European countries. However, no study broadly assessed the features ... -
High Expression Level of miR-1260 Family in the Peripheral Blood of Patients with Ovarian Carcinoma
(BMC, 2021)The most common gynecologic cancers detected in women in Turkey are uterine cancer, ovarian cancer, and cervical cancer. These data reported that a mean of 3800 individuals were diagnosed with uterine cancer, 2790 were ... -
Higher expression of the novel gene upregulated gene 4 in two acute lymphoblastic leukemia patients with poor prednisolone response
(Karger, 2012)Elucidation of the molecular mechanisms of leukemogenesis is important for a better understanding of the prognosis of acute lymphoblastic leukemia (ALL). Studies have shown that the expression of upregulated gene 4 (URG4), ... -
Higher-order structure of personality and mental health: Does general affectivity matter?
(Taylor & Francis, 2014)The higher order personality model, namely the Big Two, was tested in 2 studies (Ns = 878 and 467, respectively) by controlling for the effects of both general affectivity and common method variance. Study 2 also examined ... -
Higher-order Traits and Happiness in the Workplace: The Importance of Occupational Project Scale for the Evaluation of Characteristic Adaptations
(Taylor & Francis, 2017)This study attempts to explain the relationship between job satisfaction and the Big Two, Stability and Plasticity, which are the higher-order traits of Big Five. Occupational Project, a narrative construct, was considered ... -
Highly stable and reusable immobilized formate dehydrogenases: Promising biocatalysts for in situ regeneration of NADH
(2016)This study aimed to prepare robust immobilized formate dehydrogenase (FDH) preparations which can be used as effective biocatalysts along with functional oxidoreductases, in which in situ regeneration of NADH is required. ... -
Histopathological View of Benign Essential Blepharospasm: Orbicularis Oculi Hormone Receptor Levels
(Kare Publishing, 2023)Objectives: Benign essential blepharospasm (BEB) is a focal dystonia characterized by involuntary contractions of the orbicularis oculi and periocular muscles. We aimed to investigate the effects of muscle receptor levels ... -
HNF1A-MODY Mutations in Nuclear Localization Signal Impair HNF1A-Import Receptor KPNA6 Interactions
(Springer, 2021)Mutations in hepatocyte nuclear factor (HNF)1A gene cause the most common form of Maturity-onset diabetes of the young (MODY), a monogenic subtype of diabetes mellitus. Functional characterization of mutant proteins reveals ... -
Host-Guest Interactions of Caffeic Acid Phenethyl Ester with β-Cyclodextrins
(American Chemical Society, 2023)The aim of this study is to improve the solubility, chemical stability, and in vitro biological activity of caffeic acid phenethyl ester (CAPE) by forming inclusion complexes with β-cyclodextrin (β-CD) and hydroxypropyl- ... -
Human papillomavirus prevalence and genotype distribution among Turkish women with or without cervical lesion
(Wolters Kluwer Medknow Publications, 2018)Context: Human papillomavirus (HPV) infection is the main cause of cervical cancer, but the risk is associated with the various HPV genotypes which may be found in women with or without clinical findings. Aims: We aimed ... -
Identification of candidate genes in a family with cancer overload by whole-exome sequencing
(Turkish National Pediatric Society, 2022)Background. Approximately 120 out of every 1 million children in the world develop cancer each year. In Turkey, 2500-3000 children are diagnosed with new cancer each year. The causes of childhood cancer have been studied ... -
Impact of Cerebral Microbleeds in Stroke Patients with Atrial Fibrillation
(John Wiley and Sons Inc, 2023)Objectives: Cerebral microbleeds are associated with the risks of ischemic stroke and intracranial hemorrhage, causing clinical dilemmas for antithrombotic treatment decisions. We aimed to evaluate the risks of intracranial ... -
The impact of COVID-19 on construction labor productivity: the case of Turkey
(Emerald Group Holdings Ltd., 2022)Purpose: The aim of this study is to measure the impact of the factors affecting construction labor productivity by focusing on different types of construction works during and after the COVID-19 pandemic in Turkey, as ...
