Kurum Yazarı "Uba, Abdullahi Ibrahim" PubMed İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Adding New Scientific Evidences on the Pharmaceutical Properties of Pelargonium quercetorum Agnew Extracts by Using In Vitro and In Silico Approaches
Chiavaroli, Annalisa; Libero, Maria Loreta; Di Simone, Simonetta Cristina; Acquaviva, Alessandra; Nilofar, Lucia; Uba, Abdullahi Ibrahim (MDPI, 2023)Pelargonium quercetorum is a medicinal plant traditionally used for treating intestinal worms. In the present study, the chemical composition and bio-pharmacological properties of P. quercetorum extracts were investigated. ... -
Appraisals on the chemical characterization and biological potentials of Ranunculus constantinopolitanus extracts using chromatographic, computational, and molecular network approaches
Uba, Abdullahi Ibrahim; BESIII Collaboration (Elsevier Ltd, 2023)In this context, phytochemicals were extracted from Ranunculus constantinopolitanus using ethyl acetate (EA), ethanol, ethanol/water (70%), and water solvent. The analysis encompassed quantification of total phenolic and ... -
Assessing the Chemical Profile and Biological Potentials of Tamarix aphylla (L.) H.Karst. and Tamarix senegalensis DC. by In Vitro, In Silico, and Network Methodologies
Mahadi, Tawsol M.; Yagi, Sakina; Nilofar; Caprioli, Giovanni; Piatti, Diletta; Ricciutelli, Massimo; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Eltigani, Sayadat M.; Zengin, Gokhan (Springer, 2024)The present study aimed to investigate the chemical profile, antioxidant, and enzyme inhibition properties of extracts from fruits and aerial parts (leaves and twigs) of Tamarix aphylla and T. senegalensis. Hexane, ... -
Bacteriophage genome engineering for phage therapy to combat bacterial antimicrobial resistance as an alternative to antibiotics
Usman, Sani Sharif; Uba, Abdullahi Ibrahim; Christina, Evangeline (SPRINGER, 2023)Bacteriophages (phages) are viruses that mainly infect bacteria and are ubiquitously distributed in nature, especially to their host. Phage engineering involves nucleic acids manipulation of phage genome for antimicrobial ... -
Chemical characterization of three different extracts obtained from Chelidonium majus L. (Greater celandine) with insights into their in vitro, in silico and network pharmacological properties
Terzic, Milena; Fayez, Shaimaa; Fahmy, Nouran M.; Eldahshan, Omayma A.; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Selvi, Selami; Nilofar; Koyuncu, Ismail; Yuksekdag, Ozgur; Zengin, Gokhan (Elsevier B.V., 2024)Plant species C. majus, which is a very rich source of secondary metabolites, was used to obtain extracts, using a conventional extraction technique. For the extraction of bioactive molecules, three solvents were used: ... -
Chemical exploration of different extracts from Phytolacca americana leaves and their potential utilization for global health problems: ın silico and network pharmacology validation
Uba, Abdullahi Ibrahim; BESIII Collaboration (Taylor and Francis Ltd., 2024)Phytolacca americana L. is of great interest as a traditional additive in various folk remedies in several countries, including Turkey. We aimed to determine the chemical profile (assisted by high-Performance liquid ... -
Comparative GC-MS Analysis of Fresh and Dried Curcuma Essential Oils with Insights into Their Antioxidant and Enzyme Inhibitory Activities
Fahmy, Nouran M.; Fayez, Shaimaa; Uba, Abdullahi Ibrahim; Shariati, Mohammad Ali; Aljohani, Abdullah S. M.; El-Ashmawy, Ibrahim M.; Batiha, Gaber El-Saber; Eldahshan, Omayma A.; Singab, Abdel Nasser; Zengin, Gokhan (MDPI, 2023)Species belonging to the Zingiberaceae family are of high nutritional, industrial, and medicinal values. In this study, we investigated the effect of processing steps (fresh vs. dried milled rhizomes) and extraction ... -
Comparative Study on the Chemical Profile, Antioxidant Activity, and Enzyme Inhibition Capacity of Red and White Hibiscus sabdariffa Variety Calyces
Yagi, Sakina; Uba, Abdullahi Ibrahim; Sinan, Kouadio Ibrahime; Piatti, Diletta; Sagratini, Gianni; Caprioli, Giovanni; Eltigani, Sayadat M.; Lazarova, Irina; Zengin, Gokhan (American Chemical Society, 2023)Hibiscus sabdariffa L. (Family: Malvaceae) is believed to be domesticated by the people of western Sudan sometime before 4000 BC for their nutritional and medicinal properties. This study aimed to investigate the chemical ... -
Computational analysis of drug resistance of taxanes bound to human β-tubulin mutant (D26E)
Uba, Abdullahi Ibrahim; Bui-Linh, Candice; Thornton, Julianne M.; Olivieri, Michael; Wu, Chun (Elsevier Inc., 2023)The single-point mutation D26E in human β-tubulin is associated with drug resistance seen with two anti-mitotic taxanes (paclitaxel and docetaxel) when used to treat cancers. The molecular mechanism of this resistance ... -
Elucidating the chemical profile and biological studies of Verbascum diversifolium Hochst. extracts
Uba, Abdullahi Ibrahim; BESIII Collaboration (Frontiers Media SA, 2024)The present study was designed to evaluate the chemical composition, antioxidant, enzyme inhibition and cytotoxic properties of different extracts from aerial parts of V. diversifolium (family Scrophulariaceae), a plant ... -
Extractions of aerial parts of Hippomarathrum scabrum with conventional and green methodologies
Duran, Tugce; Uba, Abdullahi Ibrahim; Nilofar; Cvetanović Kljakić, Aleksandra; Božunović, Jelena; Gašić, Uroš; Bouyahya, Abdelhakim; Yıldiztugay, Evren; Ferrante, Claudio; Zengin, Gokhan (John Wiley and Sons Inc, 2023)Hippomarathrum scabrum L. is an endemic medicinal plant in Turkey; however, there have been few studies investigating the phytochemistry and biological properties of these plants has not been investigated. The aim of this ... -
In the quest for histone deacetylase inhibitors: current trends in the application of multilayered computational methods
Zengin, Gokhan (SPRINGER WIEN, 2023)Histone deacetylase (HDAC) inhibitors have gained attention over the past three decades because of their potential in the treatment of different diseases including various forms of cancers, neurodegenerative disorders, ... -
In Vitro and Molecular Docking Evaluation of Larvicidal Effects of Essential Oils of Five Aromatic Plants on the Fall Armyworm Spodoptera frugiperda JE. Smith (Lepidoptera: Noctuidae) from Ivory Coast
Kobenan, Koffi Christophe; Kouadio, Ibrahime Sinan; Kouakou, Malanno; Silvie, Pierre; Kouadio, Kra Norbert Bini; N'goran, Kouadio Emmanuel; Kouakou, Brou Julien; Amangoua, Nogbou Ferdinand; Tehia, Kouakou Etienne; Uba, Abdullahi Ibrahim; Zengin, Gokhan (WILEY-V C H VERLAG GMBH, 2023)Faced with the serious consequences resulting from the abusive and repeated use of synthetic chemicals, today rethinking crop protection is more than necessary. It is in this context that the essential oils of the Lamiaceae ... -
LC-MS/MS and GC-MS profiling, antioxidant, enzyme inhibition, and antiproliferative activities of Thymus leucostomus HAUSSKN. & VELEN. extracts
Fayez, Shaimaa; Fahmy, Nouran M.; Zengin, Gokhan; Yagi, Sakina; Uba, Abdullahi Ibrahim; Eldahshan, Omayma A.; Koyuncu, Ismail; Temiz, Ebru; Dall'Acqua, Stefano; Sut, Stefania; Selvi, Selami (WILEY-V C H VERLAG GMBH, 2023)The chemical composition as well as antioxidant, antiproliferative, and enzyme inhibition activities of extracts from aerial parts of Thymus leucostomus H ausskn. & V elen. obtained with hexane, methanol, and water were ... -
Phenolic compounds as histone deacetylase inhibitors: binding propensity and interaction insights from molecular docking and dynamics simulations
Uba, Abdullahi Ibrahim; Zengin, Gokhan (SPRINGER WIEN, 2023)Histone deacetylases are well-established target enzymes involved in the pathology of different diseases including cancer and neurodegenerative disorders. The approved HDAC inhibitor drugs are associated with cellular ... -
Phenolic compounds as potential adenosine deaminase inhibitors
Adenosine deaminase (ADA) is a Zn2+-containing enzyme that catalyzes the irreversible deamination of adenosine to inosine or deoxyadenosine to deoxyinosine. In addition to this enzymatic function, ADA mediates cell-to-cell ... -
Screening for Chemical Characterization and Pharmacological Properties of Different Extracts from Nepeta italica
Acquaviva, Alessandra; Di Simone, Simonetta Cristina; Nilofar, Abdelhakim; Bouyahya, Abdelhakim; Zengin, Gokhan; Recinella, Lucia; Leone, Sheila; Brunetti, Luigi; Uba, Abdullahi Ibrahim; Guler, Osman; Balos, Maruf; Cakilcioglu, Ugur; Menghini, Luigi; Ferrante, Claudio; Orlando, Giustino; Libero, Maria Loreta; Chiavaroli, Annalisa (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Plants from the Nepeta genus have been proved to possess different pharmacological properties, among which are antimicrobial, antioxidant, anti-inflammatory, analgesic, and cytotoxic effects. Nepeta italica is a medicinal ... -
Uncovering chemical profiles, biological potentials, and protection effect against ECM destruction in H2O2-treated HDF cells of the extracts of Stachys tundjeliensis
Kurt-Celep, Inci; Zheleva-Dimitrova, Dimitrina; Sinan, Kouadio Ibrahime; Uba, Abdullahi Ibrahim (John Wiley and Sons Inc, 2023)The genus Stachys L., one of the largest genera of the Lamiaceae family, is highly represented in Turkey. This study was conducted to determine the bio-pharmaceutical potential and phenolic contents of six different extracts ...