Yazar "Zengin, Gokhan" için listeleme
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LC-MS/MS and GC-MS profiling, antioxidant, enzyme inhibition, and antiproliferative activities of Thymus leucostomus HAUSSKN. & VELEN. extracts
Fayez, Shaimaa; Fahmy, Nouran M.; Zengin, Gokhan; Yagi, Sakina; Uba, Abdullahi Ibrahim; Eldahshan, Omayma A.; Koyuncu, Ismail; Temiz, Ebru; Dall'Acqua, Stefano; Sut, Stefania; Selvi, Selami (WILEY-V C H VERLAG GMBH, 2023)The chemical composition as well as antioxidant, antiproliferative, and enzyme inhibition activities of extracts from aerial parts of Thymus leucostomus H ausskn. & V elen. obtained with hexane, methanol, and water were ... -
Marine Streptomyces sp. PGC 39
Ahmad, Rabbia; Tousif, Muhammad Imran; Nazir, Mamona; Yaqoob, Asma; Shah, Syed Adnan Ali; Zengin, Gokhan; Uba, Abdullahi Ibrahim; Muhammad, Shabbir (Elsevier Ltd, 2024)Macrolidycin (1) and pyrachlomycin (2) were isolated from the culture broth of the marine bacterium Streptomyces sp. GSCWU 39. The isolates were characterized due to 1D and 2D-NMR spectral analyses and high resolution mass ... -
Novel benzene sulfonamide-piperazine hybrid compounds
Buran, Kerem; Inan, Yigit; Uba, Abdullahi Ibrahim; Zengin, Gokhan (Walter de Gruyter GmbH, 2024)Benzene sulfonamides are an important biological substituent for several activities. In this study, hybridization of benzene sulfonamide with piperazine derivatives were investigated for their antioxidant capacity and ... -
Phenolic compounds as histone deacetylase inhibitors: binding propensity and interaction insights from molecular docking and dynamics simulations
Uba, Abdullahi Ibrahim; Zengin, Gokhan (SPRINGER WIEN, 2023)Histone deacetylases are well-established target enzymes involved in the pathology of different diseases including cancer and neurodegenerative disorders. The approved HDAC inhibitor drugs are associated with cellular ... -
Phenolic compounds as potential adenosine deaminase inhibitors
Adenosine deaminase (ADA) is a Zn2+-containing enzyme that catalyzes the irreversible deamination of adenosine to inosine or deoxyadenosine to deoxyinosine. In addition to this enzymatic function, ADA mediates cell-to-cell ... -
Screening for Chemical Characterization and Pharmacological Properties of Different Extracts from Nepeta italica
Acquaviva, Alessandra; Di Simone, Simonetta Cristina; Nilofar, Abdelhakim; Bouyahya, Abdelhakim; Zengin, Gokhan; Recinella, Lucia; Leone, Sheila; Brunetti, Luigi; Uba, Abdullahi Ibrahim; Guler, Osman; Balos, Maruf; Cakilcioglu, Ugur; Menghini, Luigi; Ferrante, Claudio; Orlando, Giustino; Libero, Maria Loreta; Chiavaroli, Annalisa (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Plants from the Nepeta genus have been proved to possess different pharmacological properties, among which are antimicrobial, antioxidant, anti-inflammatory, analgesic, and cytotoxic effects. Nepeta italica is a medicinal ... -
Unraveling the chemical profile, antioxidant, enzyme inhibitory, cytotoxic potential of different extracts from Astragalus caraganae
Kurt-Celep, Inci; Zengin, Gokhan; Uba, Abdullahi I.; Caprioli, Giovanni; Mustafa, Ahmed M.; Angeloni, Simone; Cakilcioglu, Ugur; Guler, Osman; Kaplan, Alevcan; Sharmeen, Jugreet; Mahomoodally, Mohamad F. (WILEY-V C H VERLAG GMBH, 2023)Six extracts (water, ethanol, ethanol-water, ethyl acetate, dichloromethane, and n-hexane) of Astragalus caraganae were studied for their biological activities and bioactive contents. Based on high-performance liquid ... -
Unveiling the potential antibacterial mechanism of Melaleuca cajuputi leaf extract by cell morphology studies and molecular docking analysis
Isah, Musa; Wan Abdul Wahab, Wan-Nor-Amilah; Abdullah, Hasmah; Jamil, Shajarahtunnur; Sul'ain, Mohd Dasuki; Uba, Abdullahi Ibrahim; Zengin, Gokhan; Lahiri, Dibyajit; Edinur, Hisham Atan; Wan Ishak, Wan Rosli (Springer, 2024)The antimicrobial properties of the Melaleuca cajuputi plant have been documented. However, the underlying antimicrobial mechanisms remain relatively unexplored. Thus, this study aimed to investigate the antibacterial ...