Yazar "Çubuk, Hasan" için listeleme
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Comparison of Clinically Approved Molecules on SARS-CoV-2 Drug Target proteins: A Molecular Docking Study
Çubuk, Hasan; Özbil, Mehmet (TUBITAK, 2021)The new type of coronavirus, SARS-CoV-2 has affected more than 22.6 million people worldwide. Since the first day the virus was spotted in Wuhan, China, numerous drug design studies have been conducted all over the globe. ... -
Computational Analysis of Functional Monomers Used in Molecular Imprinting for Promising Covid-19 Detection
Çubuk, Hasan; Özbil, Mehmet; Hatır Çakır, Pınar (Elsevier, 2021)Today, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently caused a severe outbreak worldwide. There are still several challenges in COVID-19 diagnoses, such as limited reagents, equipment, and long ... -
In Silico Analysis of SARS-CoV-2 Spike Protein N501Y and N501T Mutation Effects on Human ACE2 Binding
Çubuk, Hasan; Özbi·l, Mehmet (Elsevier Inc., 2022)The SARS-CoV-2 is an RNA-based virus and the most vital step of its survival is the attachment to hACE2 through its spike protein. Although SARS-CoV-2 has the ability to maintain high accurate replication and it can be ... -
A Review of Functional Characterization of Single Amino Acid Change Mutations in HNF Transcription Factors in MODY Pathogenesis
Çubuk, Hasan; Yalçın Çapan, Özlem (Springer, 2021)Mutations in HNF transcription factor genes cause the most common subtypes of maturity-onset of diabetes of youth (MODY), a monogenic form of diabetes mellitus. Mutations in the HNF1-alpha, HNF4-alpha, and HNF1-beta genes ...
