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dc.contributor.authorKoca Işıkçı, Elifen_US
dc.contributor.authorEvrensel, Cihanen_US
dc.contributor.authorÇaylı, Gökhanen_US
dc.contributor.authorHatır Çakır, Pınaren_US
dc.identifier.citationKoca, E. I., Evrensel, C., Cayli, G., Hatir, P. C., & Ieee. (2017). Effect of Plant Oil-Based Crosslinker on Drug Release Behaviour of Hydrogels. New York: Ieee.en_US
dc.descriptionKoca Işıkçı, Elif (Arel Author), Evrensel, Cihan (Arel Author), Hatır Çakır, Pınar (Arel Author)en_US
dc.description.abstractThermoresponsive hydrogels have great potential in biomedical applications such as drug delivery systems and tissue engineering. Synthesis of hydrogels from renewable resources attracts attention day by day. In this study special type of thermoresponsive hydrogels were synthesized. These hydrogels are cross-linked hydrophilic polymers containing some biocompatible moieties which are derived from plant oils. Renewable resources based biocompatible materials are easily accessible, cost effective and also eco-friendly. This study is focused on synthesis of thermoresponsive hydrogels by using plant oil-based crosslinker. N-Isopropylacrylamide (NIPAM) was used as thermoresponsive monomer and acrylated methyl ricinoleate (AMR) was used as plant oil-based crosslinker. The effect of crosslinker to monomer ratio on polymerization was investigated. Spectrophotometric measurements of quercetin molecule, one of the phenolic flavonoids, were performed at room temperature (RT) and body temperature (37 degrees C). It was found that quercetin molecule released from hydrogels to aqueous medium is higher at body temperature compared to room temperature and also the molar ratio of crosslinker to monomer affects the release behaviour of hydrogels significantly. Finally plant-oil based crosslinker AMR, derived from renewable sources, can be used for hydrogel synthesis instead of other commercial crosslinker.en_US
dc.relation.ispartof2017 Electric Electronics, Computer Science, Biomedical Engineerings' Meeting (EBBT)en_US
dc.subjectThermoresponsive Hydrogelsen_US
dc.subjectPlant Oilen_US
dc.subjectAcrylated Methyl Ricinoleateen_US
dc.titleEffect of Plant Oil-Based Crosslinker on Drug Release Behaviour of Hydrogelsen_US
dc.departmentMühendislik ve Mimarlık Fakültesi, Biyomedikal Mühendisliği Bölümüen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US

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