ORCID "0000-0002-8919-0482" Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed için listeleme
-
Aberrant miR-3135b and miR-1273g-3p expression in the peripheral blood samples of BRCA1/2 (±) ovarian cancer patients
Tuncer, Seref Bugra); Celik, Betul; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Pasin, Ozge; Avsar, Mukaddes; Gultaslar, Busra Kurt; Ghafour, Arash Adamnejad; Uyaroglu, Gamze; Odemis, Demet Akdeniz; Yazici, Hulya (Elsevier Ltd, 2024)Ovarian cancer (OC) ranks as the eighth most prevalent malignancy among women globally. The short non-coding RNA molecules, microRNAs (miRNAs) target multiple mRNAs and regulate the gene expression. Here in this study, we ... -
DNA methylation of KIFC1 gene in determination of histological diagnosis, prognosis and metastasis of lung cancer
Celik, Betul; Pasin, Ozge; Sen, Sena; Tuncer, Seref Bugra; Kayim, Zubeyde Yalniz; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Gultaslar, Busra Kurt; Ghafour, Arash Adamnejad; Yazici, Hulya; Olgac, Necat Vakur (ELSEVIER GMBH, 2023)Background: One of the main features of cancer, especially lung cancer (LC), is abnormal cell division. Abnormal expression of kinesin family member C1 (KIFC1/HSET), which is involved in mitotic cell division and ensures ... -
Evaluation of BRCA1/2 Gene Mutations in Patients With High-Risk Breast and/or Ovarian Cancer in Turkey
Akdeniz Ödemiş, Demet; Çelik, Betül; Kılıç Erciyas, Seda; Şükrüoğlu Erdoğan, Özge; Tuncer, Şeref Buğra; Kurt Gültaşlar, Büşra; Adamnejad Ghafour, Arash; Saip, Pınar; Yazıcı, Hülya (De Gruyter, 2022)Objectives To find BRCA1/2 test selection criteria unique to the Turkish population, as well as to provide the BRCA1/2 gene mutation distributions of patient population to the literature. Methods Genetic counseling was ... -
Germline mutational variants of Turkish ovarian cancer patients suspected of Hereditary Breast and Ovarian Cancer (HBOC) by next-generation sequencing
Tuncer, Seref Bugra; Celik, Betul; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Gultaslar, Busra Kurt; Odemis, Demet Akdeniz; Avsar, Mukaddes; Sen, Fatma; Saip, Pinar Mualla; Yazici, Hulya (Elsevier GmbH, 2024)Hereditary Breast and Ovarian Cancer (HBOC) syndrome is characterized by an increased risk of developing breast cancer (BC) and ovarian cancer (OC) due to inherited genetic mutations. Understanding the genetic variants ... -
Identification of candidate genes in a family with cancer overload by whole-exome sequencing
Odemis, Demet Akdeniz; Kebudi, Rejin; Hassani, Masoumeh; Celik, Betul; Tuncer, Seref Bugra; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Bay, Sema Buyukkapu; Yazici, Hulya (Turkish National Pediatric Society, 2022)Background. Approximately 120 out of every 1 million children in the world develop cancer each year. In Turkey, 2500-3000 children are diagnosed with new cancer each year. The causes of childhood cancer have been studied ... -
Investigation of the methylation changes in the promoter region of RB1 gene in retinoblastoma
Erdogan, Ozge Sukruoglu; Odemis, Demet Akdeniz; Kayim, Zubeyde Yalniz; Gurbuz, Orkun; Tuncer, Seref Bugra; Kilic, Seda; Celik, Betul; Tuncer, Samuray; Bay, Sema Buyukkapu; Kebudi, Rejin; Yazici, Hulya (Elsevier GmbH, 2024)Retinoblastoma is an infrequent neoplasm that arises during childhood from retinal nerve cells and is attributed to the biallelic inactivation of the RB1 gene. In conjunction with anatomical anomalies, it is widely ... -
miR-3653-3p Expression in PBMCs: Unveiling the Diagnostic Potential for Ovarian Cancer
Delek, Fatma Seher Pektopal; Tuncer, Seref Bugra; Odemis, Demet Akdeniz; Erciyas, Seda Kilic; Erdogan, ozge Sukruoglu; Saip, Pinar; Yazici, Hulya (Springer, 2024)Ovarian cancer is typically diagnosed at an advanced stage, recurs early and often, and currently lacks effective treatment. Therefore, overall survival and progression-free survival are relatively short for this disease. ... -
Prenatal Parental Emotion Regulation Difficulties and Infants' Communication Skills
Ada, Figen Eroglu; Sendil, Telat Gul; uncer, Seref Bugra; Yazici, Hulya (HOGREFE AG-HOGREFE AG SUISSE, 2023)Konferans öğesi -
RB1 gene mutations and genetic spectrum in retinoblastoma cases
Odemis, Demet Akdeniz; Kebudi, Rejin; Bayramova, Jamila; Erciyas, Seda Kilic; Turkcan, Gozde Kuru; Tuncer, Seref Bugra; Erdogan, Ozge Sukruoglu; Celik, Betul; Gultaslar, Busra Kurt; Bay, Sema Buyukkapu; Tuncer, Samuray; Yazici, Hulya (LIPPINCOTT WILLIAMS & WILKINS, 2023)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
SARKOM PATOGENEZİNDE ETKİLİ OLABİLECEK YENİ ADAY GENLERİN ARAŞTIRILMASI
Ödemiş, Demet Akdeniz; Kebudi, Rejin; Özdenoğlu, Fazilet Yıldız; Çelik, Betül; Tunçer, Şeref Buğra; Erciyas, Seda Kilic; Erdoğan, Özge Şükrüoğlu; Bay, Sema Buyukkapu; Yazıcı, Hülya (İstanbul Üniversitesi, 2023)Amaç: Nükleer tıpta radyonüklit tedavilerde çalışan radyasyon görevlilerinin uzun dönemde maruz kaldığı radyasyon dozlarının belirlenmesi ve rutin olarak yapılan her bir tedavi prosedürünün bu dozlara katkısının belirlenmesi ... -
Tuberous Sclerosis Complex and Cancer
Dogan, Tunay; Yazici, Hulya (KARE PUBL, 2023)Tuberous sclerosis complex (TSC) is a neurocutaneous syndrome that can affect multiple organ systems such as the brain, heart, and lung, and neurological disorders such as autism spectrum disorder and mental retardation ...