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Toplam kayıt 20, listelenen: 11-20
Computational analysis of drug resistance of taxanes bound to human β-tubulin mutant (D26E)
(Elsevier Inc., 2023)
The single-point mutation D26E in human β-tubulin is associated with drug resistance seen with two anti-mitotic taxanes (paclitaxel and docetaxel) when used to treat cancers. The molecular mechanism of this resistance ...
Chemical Characterization of Different Extracts from Artemisia annua and Their Antioxidant, Enzyme Inhibitory and Anti-Inflammatory Properties
(John Wiley and Sons Inc, 2023)
Artemisia annua L. (Asteraceae Family) is an important plant in Asia that has been used for treating different diseases, including fever due to malaria, wounds, tubercolisis, scabues, pain, convulsions, diabetes, and ...
Antioxidant, enzyme inhibition, toxicity, and molecular docking analysis of Melaleuca cajuputi leaf extract and fractions
(Visagaa Publishing House, 2024)
Melaleuca cajuputi plant has piqued the interest of researchers due to its pharmacological properties. However, there is scarce information regarding its enzyme inhibitory effects and possible mechanism of action. Thus, ...
Integration of chemical characterization, biological activities, and network pharmacology of different extracts from Syzygium rowlandii
(ELSEVIER, 2024)
The leaves and stem barks of Syzygium rowlandii, were considered as sources of biologically active compounds. Using the ultrasound-assisted extraction with different solvents, we obtained three types of extracts (ethyl ...
Chemical exploration of different extracts from Phytolacca americana leaves and their potential utilization for global health problems: ın silico and network pharmacology validation
(Taylor and Francis Ltd., 2024)
Phytolacca americana L. is of great interest as a traditional additive in various folk remedies in several countries, including Turkey. We aimed to determine the chemical profile (assisted by high-Performance liquid ...
Marine Streptomyces sp. PGC 39
(Elsevier Ltd, 2024)
Macrolidycin (1) and pyrachlomycin (2) were isolated from the culture broth of the marine bacterium Streptomyces sp. GSCWU 39. The isolates were characterized due to 1D and 2D-NMR spectral analyses and high resolution mass ...
Integrating chemical analysis with in vitro, in silico, and network pharmacology to discover potential functional compounds from Marrubium astracanicum subsp. macrodon
(Elsevier B.V., 2024)
The members of the genus Marrubium are of great interest because they contain biologically active compounds. With in this mind, we aimed to examine the chemical profiles and biological activities (antioxidant, enzyme ...
Assessing the Chemical Profile and Biological Potentials of Tamarix aphylla (L.) H.Karst. and Tamarix senegalensis DC. by In Vitro, In Silico, and Network Methodologies
(Springer, 2024)
The present study aimed to investigate the chemical profile, antioxidant, and enzyme inhibition properties of extracts from fruits and aerial parts (leaves and twigs) of Tamarix aphylla and T. senegalensis. Hexane, ...
Chemical characterization of three different extracts obtained from Chelidonium majus L. (Greater celandine) with insights into their in vitro, in silico and network pharmacological properties
(Elsevier B.V., 2024)
Plant species C. majus, which is a very rich source of secondary metabolites, was used to obtain extracts, using a conventional extraction technique. For the extraction of bioactive molecules, three solvents were used: ...
Exploring the composition and potential uses of four hops varieties through different extraction techniques
(Elsevier Ltd, 2024)
Hydrophilic, lipophilic extracts and essential oil of four hops varieties from Slovenia were examined in this study. Lipophilic extracts were obtained by supercritical extraction (SFE), while for hydrophilic extracts ...