Başlık için Moleküler Biyoloji ve Genetik Bölümü Diğer Yayınlar Koleksiyonu listeleme
Toplam kayıt 15, listelenen: 1-15
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Aktif Bölge Mimarisinin Anlaşılması Temelinde, NAD + Bağımlı Mutant Candida methylica Format Dehidrogenaz Enziminin Spesifik Aktivitesinin Arttırılması
(TÜBİTAK KBAG Proje, 2023)Format dehidrogenaz enzimi (FDH), endüstriyel biyokatalizörler arasında son yıllarda en çok dikkat çeken enzimlerden biridir. Özellikle NAD(P)+ bağımlı FDH, gerçekleştirdiği reaksiyonun düşük redoks potansiyeli nedeniyle ... -
Bacteriophage genome engineering for phage therapy to combat bacterial antimicrobial resistance as an alternative to antibiotics
(SPRINGER, 2023)Bacteriophages (phages) are viruses that mainly infect bacteria and are ubiquitously distributed in nature, especially to their host. Phage engineering involves nucleic acids manipulation of phage genome for antimicrobial ... -
A correlation between the genotype and clinical course in hemophilia B patients
(Wiley, 2018-02)… -
Epigenetics in Bladder Cancer: A Review of the Literature
(Kare Publishing, 2021)Bladder cancer (BC) is the 10th most frequent type of cancer worldwide, with around 549.000 new cases and 200.000 deaths/year and it has the highest incidence rates with a strong male and elderly predominance. Besides, BC ... -
Gene therapy in haemophilia: literature review and regional perspectives for Turkey
(SAGE Publications Ltd, 2022)Haemophilia is an X-linked lifelong congenital bleeding disorder that is caused by insufficient levels of factor VIII (FVIII; haemophilia A) or factor IX (FIX; haemophilia B) and characterized by spontaneous and trauma-related ... -
In Silico Analysis of SARS-CoV-2 Spike Protein N501Y and N501T Mutation Effects on Human ACE2 Binding
(Elsevier Inc., 2022)The SARS-CoV-2 is an RNA-based virus and the most vital step of its survival is the attachment to hACE2 through its spike protein. Although SARS-CoV-2 has the ability to maintain high accurate replication and it can be ... -
İnsan p60-katanin Proteininin, Bitki RIC1 ve İnsan Homoloğu Kiaa1432 Proteinleri ile Etkileşiminin Tespiti & Etkileşimin Mikrotubuller Üzerinde Fonksiyonel Analizi
(TÜBİTAK KBAG Proje, 2023)Mikrotubuller ihtiyaç durumuna göre uzayıp–kısalabilen, yeniden organize olabilen dinamik yapılı polimerlerdir. Mikrotubul organizasyonu, bölünen hücrelerde mitoz, post-mitotik nöronlarda akson/dendrit yapılarının ... -
Lack of association of plasma factor XI with bleeding and report of two novel factor VII mutations
(Pergamon-Elsevier Science, 2016)7th International Eurasian Hematology Congress -
Neuroprotective strategies against calpain-mediated neurodegeneration
(DOVE MEDICAL PRESS LTD, 2015)Calpains are calcium-dependent proteolytic enzymes that have deleterious effects on neurons upon their pathological over-activation. According to the results of numerous studies to date, there is no doubt that abnormal ... -
A Review of Functional Characterization of Single Amino Acid Change Mutations in HNF Transcription Factors in MODY Pathogenesis
(Springer, 2021)Mutations in HNF transcription factor genes cause the most common subtypes of maturity-onset of diabetes of youth (MODY), a monogenic form of diabetes mellitus. Mutations in the HNF1-alpha, HNF4-alpha, and HNF1-beta genes ...
