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dc.contributor.authorKurt, Pınaren_US
dc.contributor.authorEmek Savaş, Derya Durusuen_US
dc.contributor.authorBatum, Kübraen_US
dc.contributor.authorTurp, Bilgeen_US
dc.contributor.authorGüntekin, Baharen_US
dc.contributor.authorKarşıdağ, Sibelen_US
dc.contributor.authorGülmen Yener, Görseven_US
dc.identifier.citationKurt, P., Emek Savaş, D. D., Batum, K., Turp, B., Güntekin, B., Karşıdağ, S., Gülmen Yener, G. (2014). Patients with Mild Cognitive impairment display reduced auditory event-related delta oscillatory responses. Behavioural Neurology. 2014, 1-11.en_US
dc.descriptionKurt, Pınar (Arel Author)en_US
dc.description.abstractBackground. Event-related oscillations (ERO) may provide a useful tool for the identification of cognitive deficits in mild cognitive impairment (MCI) and Alzheimer’s disease (AD). In the present study, we investigate peak-to-peak amplitude of auditory eventrelated delta oscillations of MCI subjects. Method. The study included twenty-two consecutive patients with MCI recruited in neurology clinic and 21 age- and education-matched normal elderly controls. A classical auditory oddball paradigm was used in the experiments. EEG was recorded from F3, Fz, F4, C3, Cz, C4, P3, Pz, P4, O1, Oz, and O2 locations. The maximum peak-to-peak amplitudes for each subject’s averaged delta response (0.5–2.2 Hz) were measured. Results. The amplitudes between groups differed significantly at the frontal and mid-centroparietal locations. ANOVA on delta responses revealed a significant effect for groups (F(1.41) = 4.84, ?? = 0.033), indicating a larger delta response for healthy controls than MCI subjects. Post hoc comparisons revealed that peak-to-peak delta response was significantly larger for healthy controls than for MCI over electrode sites F3, Fz, F4, Cz, C4, and Pz. Discussion. Event-related delta frequency band seems to be the most affected oscillatory response in cognitive impairment due to AD. Therefore, it deserves to be investigated as a candidate electrophysiological biomarker in further studies.en_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.ispartofBehavioural Neurologyen_US
dc.titlePatients with Mild Cognitive impairment display reduced auditory event-related delta oscillatory responsesen_US
dc.departmentİstanbul Arel Üniversitesi, Fen Edebiyat Fakültesi, Psikoloji Bölümü.en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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