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Now showing items 11-20 of 32

Comparative Study on the Chemical Profile, Antioxidant Activity, and Enzyme Inhibition Capacity of Red and White Hibiscus sabdariffa Variety Calyces

Yagi, Sakina; Uba, Abdullahi Ibrahim; Sinan, Kouadio Ibrahime; Piatti, Diletta; Sagratini, Gianni; Caprioli, Giovanni; Eltigani, Sayadat M.; Lazarova, Irina; Zengin, Gokhan (American Chemical Society, 2023)

Hibiscus sabdariffa L. (Family: Malvaceae) is believed to be domesticated by the people of western Sudan sometime before 4000 BC for their nutritional and medicinal properties. This study aimed to investigate the chemical ...

Chemical characterization of Glaucosciadum cordifolium extracts obtained by different extraction techniques and their biopharmaceutical effects

Kljakic, Aleksandra Cvetanovic; Bozunovic, Jelena; Gasic, Uros; Seebaluck-Sandoram, Roumita; Uba, Abdullahi Ibrahim; Mahomoodally, Mohamad Fawzi; Yildiztugay, Evren; Zengin, Gokhan (Elsevier Ltd, 2023)

Glaucosciadium cordifolium (Apiaceae) is traditionally used against stomach ailments, as aphrodisiac and appetizer. This study endeavored to characterize several extracts of G. cordifolium aerial parts (prepared by various ...

Phenolic compounds as potential adenosine deaminase inhibitors

Uba, Abdullahi Ibrahim; Paradis, Nicholas Joseph; Wu, Chun; Zengin, Gokhan (2023)

Adenosine deaminase (ADA) is a Zn2+-containing enzyme that catalyzes the irreversible deamination of adenosine to inosine or deoxyadenosine to deoxyinosine. In addition to this enzymatic function, ADA mediates cell-to-cell ...

Screening for Chemical Characterization and Pharmacological Properties of Different Extracts from Nepeta italica

Acquaviva, Alessandra; Di Simone, Simonetta Cristina; Nilofar, Abdelhakim; Bouyahya, Abdelhakim; Zengin, Gokhan; Recinella, Lucia; Leone, Sheila; Brunetti, Luigi; Uba, Abdullahi Ibrahim; Guler, Osman; Balos, Maruf; Cakilcioglu, Ugur; Menghini, Luigi; Ferrante, Claudio; Orlando, Giustino; Libero, Maria Loreta; Chiavaroli, Annalisa (Multidisciplinary Digital Publishing Institute (MDPI), 2023)

Plants from the Nepeta genus have been proved to possess different pharmacological properties, among which are antimicrobial, antioxidant, anti-inflammatory, analgesic, and cytotoxic effects. Nepeta italica is a medicinal ...

Computational analysis of drug resistance of taxanes bound to human β-tubulin mutant (D26E)

Uba, Abdullahi Ibrahim; Bui-Linh, Candice; Thornton, Julianne M.; Olivieri, Michael; Wu, Chun (Elsevier Inc., 2023)

The single-point mutation D26E in human β-tubulin is associated with drug resistance seen with two anti-mitotic taxanes (paclitaxel and docetaxel) when used to treat cancers. The molecular mechanism of this resistance ...

Chemical characterization and biological abilities of Anthocleista djalonensis collected from two locations of Ivory Coast

Sinan, Kouadio Ibrahime; Zengin, Gokhan; Uba, Abdullahi Ibrahim; Caprioli, Giovanni; Angeloni, Simone; Vittori, Sauro; Jugreet, Sharmeen; Etienne, Ouattara Katinan; Shariati, Mohamad Ali; Mahomoodally, Mohamad Fawzi (John Wiley and Sons Inc, 2023)

In this study, the total phenolic and flavonoid contents, HPLC-DAD detected phytochemicals, antioxidant and enzyme inhibitory potential of methanolic and aqueous (as infusion) extracts of the medicinal plant, Anthocleista ...

Chemical Characterization of Different Extracts from Artemisia annua and Their Antioxidant, Enzyme Inhibitory and Anti-Inflammatory Properties

Acquaviva, Alessandra; Nilofar; Bouyahya, Abdelhakim; Zengin, Gokhan; Di Simone, Simonetta Cristina; Recinella, Lucia; Leone, Sheila; Brunetti, Luigi; Uba, Abdullahi Ibrahim; Cakilcioğlu, Ugur; Polat, Rıdvan; Darendelioglu, Ekrem (John Wiley and Sons Inc, 2023)

Artemisia annua L. (Asteraceae Family) is an important plant in Asia that has been used for treating different diseases, including fever due to malaria, wounds, tubercolisis, scabues, pain, convulsions, diabetes, and ...

Antioxidant, enzyme inhibition, toxicity, and molecular docking analysis of Melaleuca cajuputi leaf extract and fractions

Isah, Musa; Zengin, Gokhan; Wahab, Wan-Nor-Amilah Wan Abdul; Abdullah, Hasmah; Sul’ain, Mohd Dasuki; Uba, Abdullahi Ibrahim (Visagaa Publishing House, 2024)

Melaleuca cajuputi plant has piqued the interest of researchers due to its pharmacological properties. However, there is scarce information regarding its enzyme inhibitory effects and possible mechanism of action. Thus, ...

Integration of chemical characterization, biological activities, and network pharmacology of different extracts from Syzygium rowlandii

Sinan, Kouadio Ibrahime; Sut, Stefania; Zengin, Gokhan; Dall'Acqua, Stefano; Bouyahya, Abdelhakim; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Rengasamy, Kannan R. R. (ELSEVIER, 2024)

The leaves and stem barks of Syzygium rowlandii, were considered as sources of biologically active compounds. Using the ultrasound-assisted extraction with different solvents, we obtained three types of extracts (ethyl ...

Chemical exploration of different extracts from Phytolacca americana leaves and their potential utilization for global health problems: ın silico and network pharmacology validation

Uba, Abdullahi Ibrahim; BESIII Collaboration (Taylor and Francis Ltd., 2024)

Phytolacca americana L. is of great interest as a traditional additive in various folk remedies in several countries, including Turkey. We aimed to determine the chemical profile (assisted by high-Performance liquid ...