Browsing Temel Tıp Bilimleri Bölümü Makale Koleksiyonu by Access Type "info:eu-repo/semantics/closedAccess"
Now showing items 1-15 of 15
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Acute sleep deprivation: impairment of biventricular function assesed by speckle tracking echocardiography in healthy subjects
(SPRINGER HEIDELBERG, 2023)ObjectivesSleep deprivation (SD) has been found to be associated with an increased incidence of adverse cardiovascular disease (CVD) events. The aim of this study was to investigate whether or not acute SD has a pathological ... -
Breast Cancer in East Africa: Prevalence and Spectrum of Germline SNV/Indel and CNVs in BRCA1 and BRCA2 Genes Among Breast Cancer Patients in Tanzania
(John Wiley and Sons Inc, 2022)Background: Growing prevalence and aggressiveness of breast cancer (BC) among East African women strongly indicate that the genetic risk factor implicated in the etiology of the disease may have a key role. Germline ... -
Can the Gut Microbiota Serve as a Guide to the Diagnosis and Treatment of Childhood Epilepsy?
(Elsevier Inc., 2023)Background: To investigate the activity of the gut-brain axis in the pathogenesis of childhood epilepsy and to define biomarkers capable of assisting with determining new strategies in that context. Methods: Twenty children ... -
DNA methylation of KIFC1 gene in determination of histological diagnosis, prognosis and metastasis of lung cancer
(ELSEVIER GMBH, 2023)Background: One of the main features of cancer, especially lung cancer (LC), is abnormal cell division. Abnormal expression of kinesin family member C1 (KIFC1/HSET), which is involved in mitotic cell division and ensures ... -
Effect of Breast Cancer and Brast Cancer Treatment on the Blood Serum Concentrations of Trace Elements and Selenoproteins
(Polish Society Magnesium Research, 2022)SciVal Topics Metrics Funding details Abstract Trace elements (TEs) playing critical roles in chemical events that occur at the cellular level in the body are necessary for biological processes in human health. The ... -
Genetic Alterations in Lung Cancer
(KARE PUBL, 2024)Lung cancer is the leading cause of cancer -related deaths worldwide. Due to the prevalence of late -stage diagnoses, treatment options are frequently constrained. Molecular profiling of lung cancer is crucial for the ... -
Genetic Alterations in Lung Cancer
(KARE PUBL, 2024)Lung cancer is the leading cause of cancer -related deaths worldwide. Due to the prevalence of late -stage diagnoses, treatment options are frequently constrained. Molecular profiling of lung cancer is crucial for the ... -
Germline mutational variants of Turkish ovarian cancer patients suspected of Hereditary Breast and Ovarian Cancer (HBOC) by next-generation sequencing
(Elsevier GmbH, 2024)Hereditary Breast and Ovarian Cancer (HBOC) syndrome is characterized by an increased risk of developing breast cancer (BC) and ovarian cancer (OC) due to inherited genetic mutations. Understanding the genetic variants ... -
Investigation of the methylation changes in the promoter region of RB1 gene in retinoblastoma
(Elsevier GmbH, 2024)Retinoblastoma is an infrequent neoplasm that arises during childhood from retinal nerve cells and is attributed to the biallelic inactivation of the RB1 gene. In conjunction with anatomical anomalies, it is widely ... -
Modulation of Neuronal Damage in DRG by Asprosin in a High-Glucose Environment and Its Impact on miRNA181-a Expression in Diabetic DRG
(Springer, 2024)Asprosin, a hormone secreted from adipose tissue, has been implicated in the modulation of cell viability. Current studies suggest that neurological impairments are increased in individuals with obesity-linked diabetes, ... -
Stereological Study on the Effect of Carnosine on of Purkinje Cells in the Cerebellum of Rats Exposed to 900 MHz Electromagnetic Field
(Turkish Neurosurgical Society, 2022)AIM: To evaluate the impact of carnosine on Purkinje neurons in rats exposed to a 900 Mhz electromagnetic field. MATERIAL and METHODS: This study evaluated 24 rats divided into the following three different groups: a control ... -
Stroke Risk and Antithrombotic Treatment During Follow-up of Patients With Ischemic Stroke and Cortical Superficial Siderosis
(LIPPINCOTT WILLIAMS & WILKINS, 2023)Background and ObjectivesIn patients with ischemic stroke (IS) or transient ischemic attack (TIA) and cortical superficial siderosis (cSS), there are few data regarding the risk of future cerebrovascular events and also ... -
Subcortical Volume Changes in Schizophrenia and Bipolar Disorder: A Quantitative MRI Study
(Universidad de la Frontera, 2024)Volume abnormalities in subcortical structures, including the hippocampus, amygdala, thalamus, caudate, putamen, and globus pallidus have been observed in schizophrenia (SZ) and bipolar disorder (BD), not all individuals ... -
Thyroid hormone resistance with succinate dehydrogenase-B gene mutation
(Edizioni Minerva Medica, 2022)Resistance to thyroid hormone (RTH) is characterized by non-suppressed TSH concentration despite high T4 and/or T3 levels.1 Resistance may develop at any steps in the hormone receptor binding, signaling, or intracellular ... -
A Volumetric Study of the Corpus Callosum in the Turkish Population
(Thieme Medical Publ Inc, 2021)Objective The aim of this study is to measure the average corpus callosum (CC) volume of healthy Turkish humans and to analyze the effects of gender and age on volumes, including the genu, truncus, and splenium parts of ...
